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For people with Down syndrome, family members, caregivers and professionals.

Global Medical Care Guidelines for Adults with Down Syndrome

December 2022 | Medical Care Guidelines for Adults with Down Syndrome Workgroup - Global Down Syndrome Foundation

On October 20, 2020, the Global Medical Care Guidelines for Adults with Down Syndrome were published in the Journal of the American Medical Association (JAMA) in an article called "Medical Care of Adults with Down Syndrome: A Clinical Guideline." They provide evidence-based recommendations to support healthcare providers in their care of adults with Down syndrome.

Links to the guidelines and other resources are available on the Global Medical Care Guidelines for Adults with Down Syndrome page opens in new window on the Global Down Syndrome Foundation website. Global requires users to provide their name and email address in order to download the documents. 

The guidelines are available in:

  • English
  • Spanish
  • Japanese

Resources include: 

  • Full Guidelines
  • Family-Friendly Guidelines
  • Checklist
  • Diabetes Toolkit
  • Celiac Disease Toolkit
  • Behavior Toolkit
  • Article in JAMA

The guidelines address:

  • Behavior
  • Dementia
  • Diabetes
  • Cardiovascular disease
  • Obesity
  • Atlantoaxial instability
  • Osteoporosis
  • Thyroid
  • Celiac disease

Access Medical Care Guidelines for Adults opens in new window


Information about medical care for children and adolescents with Down syndrome can be found in Health Supervision for Children and Adolescents with Down Syndrome from the American Academy of Pediatrics.

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We offer a variety of resources for people with Down syndrome, their families and caregivers and the professionals who care for and work with them. Search our collection of articles, webinars, videos, and other educational materials.

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Please note: The information on this site is for educational purposes only and is not intended to serve as a substitute for a medical, psychiatric, mental health, or behavioral evaluation, diagnosis, or treatment plan by a qualified professional. We recommend you review the educational material with your health providers regarding the specifics of your health care needs.