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For people with Down syndrome, family members, caregivers and professionals.

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Support Groups for Caregivers of Individuals with Down Syndrome and Alzheimer's Disease

Author: Various Organizations - Resource List

Alzheimer’s disease not only impacts the individual with the disease but also the individual’s family, friends, and caregivers. Several organizations provide in-person, online, and

Alzheimer's Disease Prevention and Healthy Aging in People with Down Syndrome Webinar Recording (5/18/2022)

Author: Brian Chicoine, MD - DSAW Webinar

On May 18, 2022, the Down Syndrome Association of Wisconsin hosted a webinar called "Alzheimer's Disease Prevention and Healthy Aging in People with Down Syndrome," presented

Obstructive Sleep Apnea, Cerebrovascular Disease, and Amyloid in Older Adults with Down Syndrome Across the Alzheimer's Continuum

Author: Lao et al. (2022) - Sleep Advances: A Journal of the Sleep Research Society

Abstract We determined the extent to which obstructive sleep apnea (OSA) is associated with increased cerebrovascular disease and amyloid burden, and the relation of the two processes across clinical

Loss of Skills and Alzheimer's Disease

Author: Brian Chicoine, MD - "Ask Dr. Chicoine" LuMind IDSC Foundation

Alzheimer’s disease is a form of cognitive impairment and decline in skills that is more common in people with Down syndrome. It is one, but not the only, type of cognitive impairment. In fa

How is Alzheimer's Disease Diagnosed in a Person with Down Syndrome?

Author: Brian Chicoine, MD - Medical Director, Adult Down Syndrome Center

Alzheimer’s disease is a progressive neurological condition. It is a type of dementia   . Alzheimer’s disease is characterized by microscopic changes in the brain that are

Mechanistic Analysis of Age-Related Clinical Manifestations in Down Syndrome

Author: Chen et al. - Frontiers in Aging Neuroscience (2021)

Abstract : Down syndrome (DS) is the most common genetic cause of Alzheimer's disease (AD) due to trisomy for all or part of human chromosome 21 (Hsa21). It is also associated with other pheno

Cross-Sectional Exploration of Plasma Biomarkers of Alzheimer's Disease in Down Syndrome: Early Data from the LIFE-DSR Study

Author: Hendrix et al. - Journal of Clinical Medicine (2021)

Abstract With improved healthcare, the Down syndrome (DS) population is both growing and aging rapidly. However, with longevity comes a very high risk of Alzheimer's disease (AD). The LIFE-DSR

Aging and Alzheimer's Disease in Adults with Down Syndrome Webinar Recording (11/10/2020)

Author: Brian Chicoine, MD and Katie Frank, PhD, OTR/L - Adult Down Syndrome Center

The video below is a recording of a webinar presented by Brian Chicoine, MD and Katie Frank, PhD, OTR/L on November 10, 2020. Dr. Chicoine is the co-founder and medical director of the Adult Down Synd

Alzheimer's Disease Video Journal Segment 8

Author: Adult Down Syndrome Center - Video Journal

The video below is segment 8a of our Alzheimer's Disease Video Journal, which consists of interviews with Colleen Buffington, a woman with Down syndrome who was diagnosed with Alzheimer

Alzheimer's Disease Video Journal Segment 8b

Author: Adult Down Syndrome Center - Video Journal

The video below is segment 8b of our Alzheimer's Disease Video Journal, which consists of interviews with Colleen Buffington, a woman with Down syndrome who was diagnosed with Alzheim

NTG - Early Detection and Screen for Dementia (NTG-EDSD)

Author: National Task Group on Intellectual and Developmental Disabilities Practices - Dementia Screening Tool

The National Task Group on Intellectual and Developmental Disabilities Practices (NTG) developed a screening tool called the NTG - Early Detection Screen for Dementia (NTG-EDSD). This questionnaire &a

Living with Dementia

Author: Down's Syndrome Scotland

This booklet for families and caregivers of individuals with Down syndrome discusses dementia. It is provided by Down's Syndrome Scotland (www.dsscotland.org.uk/resources/publications/).

Let's Talk about Dementia

Author: Down's Syndrome Scotland

This booklet for individuals with Down syndrome explains dementia using easy-to-read language. It is provided by Down's Syndrome Scotland (www.dsscotland.org.uk/resources/publications/).

Down Syndrome and Dementia: Advances in the Field

Author: McGlinchey, McCallion, & McCarron - Current Opinion in Psychiatry (2020)

Abstract Purpose of Review:  People with Down syndrome represent the world's largest population with a genetic risk for Alzheimer's disease. This review will provide a short s

Alzheimer's Disease Video Journal Segment 7

Author: Adult Down Syndrome Center - Video Journal

The video below is the seventh segment of our Alzheimer's Disease Video Journal, which consists of interviews with Colleen Buffington, a woman with Down syndrome who was diagnosed with Alzheim

Alzheimer's Disease Video Journal Segment 6

Author: Adult Down Syndrome Center - Video Journal

The video below is the sixth segment of our Alzheimer's Disease Video Journal, which consists of interviews with Colleen Buffington, a woman with Down syndrome who was diagnosed with Alzheimer

Today & Tomorrow: A Guide to Aging with Down Syndrome

Author: Canadian Down Syndrome Society - Resource

The resource linked below is a guidebook on aging from the Canadian Down Syndrome Society. While some of the information and recommendations are specific to Canada, the resource contains helpful infor

Keeping Connected to Someone with Memory Loss

Author: All Trust Home Care

This two-page resource provides ideas for staying connected to someone who is experiencing memory loss.

Alzheimer's Orientation Book

Author: Adult Down Syndrome Center

An orientation book can be used for people with Alzheimer’s disease or dementia to help them remember things about their daily life.

Course of Alzheimer Disease in People with Down Syndrome

Author: Chicoine, Dominiak, McGuire, Bilodeau

This is a poster that describes a small chart review study on Alzheimer's disease and Down syndrome done at the Adult Down Syndrome Center.

Down Syndrome and Alzheimer's for Medical Professionals

Author: Brian Chicoine, MD and Dennis McGuire, PhD - Webinar

The link below takes users to a registration page to view a webinar called "Down Syndrome and Alzheimer's for Medical Professionals" that was presented by Brian Chic

Seizures in People with Down Syndrome and Alzheimer's Disease

Author: Brian Chicoine, MD - Medical Director, Adult Down Syndrome Center

We were sent a question about seizures in a person with Down syndrome who developed Alzheimer’s disease. The individual continued to experience seizures despite being treated with l

Alzheimer's Disease in Down Syndrome Presentation (2/26/2019)

Author: Brian Chicoine, MD - Medical Director, Adult Down Syndrome Center

The video below is a recording of a presentation called "Alzheimer's Disease in Down Syndrome" given by Brian Chicoine, MD on February 26, 2019. He provides an overview of Al

Alzheimer's Disease Video Journal Segment 5a

Author: Adult Down Syndrome Center - Video Journal

The video below is the fifth segment of our Alzheimer's Disease Video Journal, which consists of interviews with Colleen Buffington, a woman with Down syndrome who was diagnosed with Alzheimer

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