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For people with Down syndrome, family members, caregivers and professionals.
Review our COVID-19 Resources
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Throughout the COVID-19 pandemic, the Trisomy 21 Research Society (T21RS) has conducted an international survey of COVID-19 in Down syndrome. Caregivers and clinicians of individuals with Down syndrom
On December 16, 2020, the Down Syndrome Medical Interest Group - USA issued a position statement on the COVID-19 vaccine. The position statement has been updated several times, most recently on Novemb
Abstract Adults with Down syndrome (DS) are at higher risk for severe outcomes of coronavirus disease 2019 (COVID-19) then the general population, but evidence is required to understand the risks for
Abstract: Objectives: To derive and validate risk prediction algorithms to estimate the risk of COVID-19 related mortality and hospital admission in UK adults after one or two doses of COVID
Abstract : Down syndrome (DS) is the most common genetic cause of Alzheimer's disease (AD) due to trisomy for all or part of human chromosome 21 (Hsa21). It is also associated with other pheno
In May 2021, the Down Syndrome Medical Interest Group shared a position statement titled "Response to Centers for Disease Control Mask Recommendations." This document shares
Abstract With improved healthcare, the Down syndrome (DS) population is both growing and aging rapidly. However, with longevity comes a very high risk of Alzheimer's disease (AD). The LIFE-DSR
Abstract Background: Health conditions, immune dysfunction, and premature aging associated with trisomy 21 (Down syndrome, DS) may impact the clinical course of COVID-19. Methods:&
Abstract Background: Health conditions, immune dysfunction, and premature aging associated with trisomy 21 (Down syndrome, DS) may impact the clinical course of COVID-19. Methods:
The article linked below describes the findings of a study that evaluated Down syndrome as a risk factor for death from COVID-19 through an analysis of individual-level data in a cohort study of 8.26
Abstract Background: Persons with Down syndrome (DS) are presumed to be at high risk of severe CoVID-19 due to immune dysregulation and often compromised cardiopulmonary function. Aim of the
*Please note: this article discusses viral testing used to diagnose if an individual currently has COVID-19. This article does not discuss antibody testing used to determine if an individual was expos
The Centers for Disease Control and Prevention (CDC) recommends wearing masks in public settings, such as grocery stores and pharmacies, and when around people who do not live in your household.&n
Reports of potential discrimination in medical treatment for individuals with intellectual and developmental disabilities have caused fear, anxiety, and anger within the Down syndrome community. Depar
Many organizations are compiling COVID-19 resource lists. We have included links to some of them below. The amount of information about COVID-19 can be overwhelming and can cause anxiety and
Abstract Purpose of Review: People with Down syndrome represent the world's largest population with a genetic risk for Alzheimer's disease. This review will provide a short s
Abstract Background : The specific distribution of cancers in Down syndrome (DS) calls into question the validity of screening policies for cancer surveillance as implemented for the general populatio
Abstract: Background: Women with Down syndrome have a lower breast cancer risk and significantly lower life expectancies than women without Down syndrome. Therefore, it is not clear whether
This is a poster that describes a small chart review study on Alzheimer's disease and Down syndrome done at the Adult Down Syndrome Center.
The link below takes users to a registration page to view a webinar called "Down Syndrome and Alzheimer's for Medical Professionals" that was presented by Brian Chic
Abstract The immune surveillance theory of cancer posits that the body's immune system detects and destroys randomly occurring malignant cells. This theory is based on the observation of the i
Abstract Alzheimer's disease (AD) may affect in excess of 90% of individuals with Down syndrome (DS) after age 60, due to duplication of the APP gene in trisomy of chromosome 21, with neuropat
Abstract: Collaboration between palliative care, dementia care, hospice provision, and intellectual disability services is required rather than any one of these systems working in isolation.
Abstract Purpose: The aim of this study was to investigate cancer incidence in a large cohort of persons with Down syndrome. Methods: Down syndrome was identified from th
Please note: The information on this site is for educational purposes only and is not intended to serve as a substitute for a medical, psychiatric, mental health, or behavioral evaluation, diagnosis, or treatment plan by a qualified professional. We recommend you review the educational material with your health providers regarding the specifics of your health care needs.